Dame, if I were the defence barrister, I would think it was reasonable to argue the following:
1. Reeva could have been raising her hand to her face for several reasons eg brush aside her long hair, scratch her nose etc, which would have resulted in the same injury to her hand. It didn't have to be a defence movement.
2. It's possible Reeva got up and ate something, while Oscar slept unaware. (Has happened in my house that one of us has got up for a while without the other noticing).
However, reading BBC's Twitter guy, it seems Roux suggested that the "2hours" timeframe is not exact and the pathologist conceded there could be an error of "an hour or two" in either dirction.
3.More than reasonable to assume that having realised it was Reeva he had shot in the bathroom, Oscar was in a blind panic and not thinking straight. Radiologist confirmed that Oscar was in a distraught state.
4.Guard stated that Oscar didn't speak during the first call but was crying. Security guard thought he had made the first call to Oscar and Oscar called him back, but phone records showed that Oscar had made the first call.
In security guard's first statement he said "Mr Pistorious said he's okay", but changed it in a later statement to "everything is okay".
5.No idea about this one, until we hear Oscar's evidence.
I've read too many crime thrillers and watched too many police dramas, haven't I?